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Table 1 Demographic features, clinical characteristics, and laboratory results of the two groups with and without headache

From: HMGB1, NLRP3, IL-6 and ACE2 levels are elevated in COVID-19 with headache: a window to the infection-related headache mechanism

 

COVID-19

Without Headache

n = 40

COVID-19

With Headache

n = 48

P value

Mean Age (years)

45.70 ± 12.72

47.71 ± 10.78

0.425

Women/ Men

19/21

16/32

0.176

Primary headache

3

11

0.077

Anosmia

1

7

0.066

Ageusia

1

5

0.214

Nausea

3

23

< 0.001

Loss of appetite

7

29

< 0.001

Weight loss

4

25

< 0.001

Diarrhea

7

15

0.216

Pulmonary involvement

13

31

0.003

D-dimer (mg/mL)

1.22 ± 1.18

8.42 ± 7.07

< 0.001

Hospitalization (days)

6.08 ± 1.37

8.38 ± 2.42

< 0.001

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The Journal of Headache and Pain

ISSN: 1129-2377

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