Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.
Skip to main content

Table 5 Expenditure of preventive drugs dispensed between 2018 and 2022

From: Trends and prescribing patterns of antimigraine medicines in nine major cities in China from 2018 to 2022: a retrospective prescription analysis

 

2018

2019

2020

2021

2022

Total

P1

P2

Total preventative drugs

245,363.86

281,422.20

277,575.91

327,095.25

320,843.99

1,452,301.21

0.221

–

CCBs

60,487.77 (24.65)

72,853.12 (25.89)

57,446.59 (20.70)

70,194.61 (21.46)

57,062.85 (17.79)

318,044.94 (21.90)

0.462

<  0.001

 Flunarizine

59,299.05 (24.17)

72,853.12 (25.89)

57,446.59 (20.70)

70,194.61 (21.46)

57,062.85 (17.79)

316,856.22 (21.82)

0.462

<  0.001

Antidepressants

101,538.71 (41.38)

117,488.23 (41.75)

92,735.89 (33.41)

107,734.09 (32.94)

76,892.91 (23.97)

496,389.83 (34.18)

0.462

<  0.001

 Flupentixol/melitracen

23,560.92 (9.60)

33,441.56 (11.88)

22,165.50 (7.99)

30,767.90 (9.41)

20,623.98 (6.43)

130,559.86 (8.99)

0.462

<  0.001

 Amitriptyline

1395.06 (0.57)

1405.31 (0.50)

1602.08 (0.58)

2759.29 (0.84)

1232.31 (0.38)

8394.05 (0.58)

0.807

0.398

 Escitalopram

35,524.44 (14.48)

36,671.57 (13.03)

14,199.23 (5.12)

25,490.65 (7.79)

16,238.36 (5.06)

128,124.25 (8.82)

0.462

<  0.001

Anticonvulsants

45,860.12 (18.69)

50,422.43 (17.92)

58,794.05 (21.18)

93,473.04 (28.58)

102,190.54 (31.85)

350,740.18 (24.15)

0.028

<  0.001

 Topiramate

24,308.78 (9.91)

30,299.16 (10.77)

40,037.64 (14.42)

54,532.44 (16.67)

59,100.48 (18.42)

208,278.50 (14.34)

0.028

<  0.001

 Valproate

11,673.63 (4.76)

11,790.05 (4.19)

10,083.37 (3.63)

18,657.67 (5.70)

17,593.05 (5.48)

69,797.77 (4.81)

0.462

<  0.001

CCMs

12,529.74 (5.11)

15,122.32 (5.37)

20,802.53 (7.49)

16,278.36 (4.98)

23,079.52 (7.19)

87,812.47 (6.05)

0.086

<  0.001

 Gabapentin

6346.28 (2.59)

7883.74 (2.80)

5711.74 (2.06)

3468.40 (1.06)

1703.20 (0.53)

25,113.36 (1.73)

0.086

<  0.001

 Pregabalin

6183.46 (2.52)

7238.58 (2.57)

15,090.79 (5.44)

12,809.96 (3.92)

21,376.32 (6.66)

62,699.11 (4.32)

0.086

<  0.001

Beta blockers

9643.72 (3.93)

12,800.38 (4.55)

12,341.97 (4.45)

15,395.31 (4.71)

15,588.51 (4.86)

65,769.89 (4.53)

0.086

<  0.001

 Metoprolol

4679.27 (1.91)

8064.44 (2.87)

6384.54 (2.30)

8162.081 (2.50)

8946.85 (2.79)

36,237.18 (2.50)

0.086

<  0.001

 Propranolol

1498.06 (0.61)

1228.10 (0.44)

1127.36 (0.41)

1282.85 (0.39)

1268.64 (0.40)

6405.01 (0.44)

0.807

<  0.001

Other agents

15,303.8 (6.24)

12,735.72 (4.53)

35,454.88 (12.77)

24,019.84 (7.34)

46,029.66 (14.35)

133,543.9 (9.20)

0.221

<  0.001

  1. CCBs Calcium channel blockers, CCMs calcium channel modulators. P1, P value for the trend in number of prescriptions, assessed by the Mann-Kendall trend test; P2, P value for the trend in proportion of prescriptions, assessed by the Cochran-Armitage trend test. The number of total preventative drugs for each year is the denominator of the data in that column
Back to article page

The Journal of Headache and Pain

ISSN: 1129-2377

Contact us