Table 3 Characteristics of the female study population at visit 1, stratified by headache status; n = 480, n(%), mean ± SD, median (Q1; Q3)
From: Migraine or any headaches and white matter hyperintensities and their progression in women and men
Definitive MigA+* | Probable MigA+* | All MigA+** | Definitive MigA-* | Probable MigA-* | All MigA−** | NonMigHA | NeverHA | Total | |
|---|---|---|---|---|---|---|---|---|---|
n(%) | 40 (8.3) | 30 (6.3) | 70 (14.6) | 78 (16.2) | 94 (19.6) | 172 (35.8) | 169 (35.2) | 69 (14.4) | 480 (100) |
visual disturbances*** | 38 (95.0) | 30 (100) | 68 (97.1) | ||||||
tingling/deafness*** | 12 (30.0) | 3 (10.0) | 15 (21.4) | ||||||
weakness in arm/leg*** | 3 (7.5) | 0 | 3 (4.3) | ||||||
speech disorders*** | 6 (15.0) | 3 (10.0) | 9 (12.9) | ||||||
age [years] | 58.3 ± 11.0 | 60.2 ± 12.8 | 59.1 ± 11.7 | 59.0 ± 13.2 | 57.4 ± 14.1 | 58.1 ± 13.7 | 61.8 ± 10.9 | 66.5 ± 8.2 | 60.8 ± 12.1 |
smoking never past current | 21 (52.5) | 18 (60.0) | 39 (55.7) | 40 (51.3) | 54 (57.4) | 94 (54.7) | 92 (54.4) | 42 (60.9) | 267 (55.6) |
15 (37.5) | 6 (20.0) | 21 (30.0) | 29 (37.2) | 29 (30.9) | 58 (33.7) | 50 (29.6) | 20 (29.0) | 149 (31.0) | |
4 (10.0) | 6 (20.0) | 10 (14.3) | 9 (11.5) | 11 (11.7) | 20 (11.6) | 27 (16.0) | 7 (10.1) | 64 (13.3) | |
BMI [kg/m²] | 25.9 ± 4.6 | 26.7 ± 4.0 | 26.3 ± 4.3 | 27.6 ± 5.1 | 27.3 ± 5.5 | 27.4 ± 5.3 | 27.2 ± 5.0 | 27.6 ± 4.7 | 27.2 ± 5.0 |
missing | 1 | 1 | 1 | ||||||
sport yes no | 28 (70.0) | 21 (70.0) | 49 (70.0) | 53 (67.9) | 64 (68.1) | 117 (68.0) | 118 (69.8) | 52 (75.4) | 336 (70.0) |
12 (30.0) | 9 (30.0) | 21 (30.0) | 25 (32.1) | 30 (31.9) | 55 (32.0) | 51 (30.2) | 17 (24.6) | 144 (30.0) | |
education [years] | 14.4 ± 2.3 | 14.6 ± 2.4 | 14.5 ± 2.3 | 14.5 ± 2.2 | 14.3 ± 2.4 | 14.4 ± 2.3 | 14.2 ± 2.3 | 13.7 ± 2.2 | 14.2 ± 2.3 |
missing | 1 | 1 | 2 | 2 | 3 | ||||
systolic RR [mmHg] | 123.7 ± 14.6 | 118.1 ± 15.8 | 121.3 ± 15.7 | 122.2 ± 17.4 | 124.4 ± 16.8 | 123.4 ± 17.1 | 123.0 ± 17.4 | 124.7 ± 15.9 | 123.2 ± 16.8 |
diabetes mellitus yes no | 3 (7.5) | 1 (3.3) | 4 (5.7) | 9 (11.5) | 12 (12.8) | 21 (12.2) | 15 (8.9) | 8 (11.6) | 48 (10.0) |
37 (92.5) | 29 (96.7) | 66 (94.3) | 69 (88.5) | 82 (87.2) | 151 (87.8) | 154 (91.1) | 61 (88.4) | 432 (90.0) | |
cholesterol [mg/dl] | 225.2 ± 44.5 | 206.8 ± 34.4 | 217.4 ± 41.3 | 229.7 ± 38.2 | 220.3 ± 40.6 | 224.6 ± 39.7 | 222.0 ± 38.9 | 227.9 ± 40.7 | 223.1 ± 39.8 |
missing | 1 | 1 | 2 | 2 | 4 | 1 | 6 | ||
LDL [mg/dl] | 129.5 ± 36.7 | 124.1 ± 29.3 | 127.2 ± 33.6 | 137.8 ± 34.4 | 128.3 ± 35.4 | 132.6 ± 35.2 | 128.3 ± 32.2 | 133.3 ± 36.7 | 130.4 ± 34.1 |
missing | 1 | 1 | 2 | 1 | 4 | 5 | |||
HDL [mg/dl] | 72.4 ± 14.3 | 65.4 ± 16.5 | 69.4 ± 15.5 | 71.4 ± 17.5 | 70.9 ± 18.1 | 71.1 ± 17.8 | 71.5 ± 16.6 | 71.3 ± 16.9 | 71.0 ± 16.9 |
missing | 1 | 1 | 2 | 2 | 4 | 5 | |||
WMH vol. V1 [mm3] median | 4069 | 4117 | 4082 | 3758 | 3458 | 3625 | 4125 | 4078 | 4005 |
Q1; Q3 | 2022; 7462 | 2116; 8437 | 2039; 7688 | 2051; 6594 | 2339; 6475 | 2072; 6534 | 2727; 7512 | 2842; 6091 | 2454; 6880 |
Fazekas grade (deep) low (0–1) | 26 (65.0) | 17 (56.7) | 43 (61.4) | 55 (70.5) | 64 (68.1) | 119 (69.2) | 104 (61.5) | 38 (55.1) | 304 (63.3) |
14 (35.0) | 13 (43.3) | 27 (38.6) | 23 (29.5) | 30 (31.9) | 53 (30.8) | 65 (38.5) | 31 (44.9) | 176 (36.7) | |
Fazekas grade (pv) low (0–1) | 23 (57.5) | 19 (63.3) | 42 (60.0) | 48 (61.5) | 66 (70.2) | 114 (66.3) | 100 (59.2) | 42 (60.9) | 298 (62.1) |
17 (42.5) | 11 (36.7) | 28 (40.0) | 30 (38.5) | 28 (29.8) | 58 (33.7) | 69 (40.8) | 27 (39.1) | 182 (37.9) |