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Table 3 Colocalization results of 10 significant genes from brain

From: Identifying therapeutic target genes for migraine by systematic druggable genome-wide Mendelian randomization

Gene

PPH0

PPH1

PPH2

PPH3

PPH4

BRPF3

0.067

0.008

0.035

0.003

0.888

HMGCR

0.110

0.087

0.011

0.008

0.785

TGFB3

0.045

0.001

0.052

0.000

0.902

FGFRL1

0.000

0.000

0.081

0.001

0.918

EPHA5

0.000

0.000

0.094

0.012

0.894

NLGN2

0.000

0.000

0.007

0.030

0.962

  1. PPH0-PPH4 represent the posterior probabilities of different hypotheses, and PPH4 > 0.75 was considered as a significant colocalization result
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The Journal of Headache and Pain

ISSN: 1129-2377

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