From: Hypersensitivity to BKCa channel opening in persistent post-traumatic headache
The following criteria are used for experimentally induced migraine-like headache: |
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Migraine-like headache must fulfill at least two of the following four characteristics: |
• Unilateral location |
• Pulsating quality |
• Moderate or severe pain intensity |
• Aggravation by or causing avoidance of routine physical activity (e.g., walking or climbing stairs) |
During headache, at least one of the following must be fulfilled: |
• Nausea and/or vomiting |
• Photophobia and phonophobia, or |
• Headache mimicking the usual headache exacerbation with migraine-like features |