Table 2 Treatment response at the LOTP
MHD, Median (IQR) | MMD, Median (IQR) | AMD, Median (IQR) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Baseline | LOT | Reduction | p-value | Baseline | LOT | Reduction | p-value | Baseline | LOT | Reduction | p-value | ||
Episodic Migraine | MO | 12 | 5.7 | -6 | < 0.0001 | 11 | 4.3 | -6.3 | < 0.0001 | 11 | 5 | -6.3 | < 0.0001 |
(10.2, 12.9) | (4.0, 8.2) | (-7.8, -3.0) | (10.0, 11.9) | (2.2, 7.0) | (-9.2, -3.8) | (10.0, 12.2) | (3.0, 6.8) | (-8.2, -4.2) | |||||
noMO | 9.3 | 6.2 | -3.3 | < 0.0001 | 8 | 4.7 | -3.3 | < 0.0001 | 7 | 4 | -1.7 | 0.0005 | |
(8.0, 11.7) | (3.7, 9.7) | (-5.3, -1.0) | (6.0, 9.3) | (3.0, 7.3) | (-5.0, -1.4) | (5.0, 8.0) | (2.7, 7.0) | (-4.3, 0.3) | |||||
All | 10 | 6 | -4.2 | < 0.0001 | 8.7 | 4.7 | -4 | < 0.0001 | 8 | 4.3 | -3.3 | < 0.0001 | |
(8.3, 12.0) | (3.7, 9.3) | (-6.4, -1.3) | (6.7, 11.1) | (2.7, 7.3) | (-6.3, -1.7) | (6.0, 10.0) | (2.9, 7.1) | (-5.8,—0.6) | |||||
Chronic Migraine | MOH | 20.3 | 12.7 | -6.7 | < 0.0001 | 15 | 8.3 | -5.4 | < 0.0001 | 15 | 8.7 | -6.3 | < 0.0001 |
(17.0, 26.0) | (7.3, 22.0) | (-13.3, -1.7) | (12.3, 20.0) | (5.7, 14.3) | (-11.3, -1.7) | (10.7, 19.0) | (5.0, 11.7) | (-9.3, -2.0) | |||||
noMOH | 20.5 | 17.2 | -3.3 | < 0.0001 | 12.6 | 7.7 | -3 | < 0.0001 | 7.5 | 5.3 | -2 | < 0.0001 | |
(16.2, 30.0) | (10.1, 29.6) | (-9.2, 0.0) | (9.0, 16.5) | (5.0, 15.8) | (-6.0, 0.0) | (5.0, 9.0) | (3.1, 7.5) | (-3.7, 0.0) | |||||
All | 20.3 | 14.7 | -5.7 | < 0.0001 | 15 | 8.3 | -4.7 | < 0.0001 | 10 | 6.3 | -3.7 | < 0.0001 | |
(16.7, 26.7) | (8.7, 24.8) | (-12.0, 0.0) | (11.0, 20.0) | (5.0, 14.7) | (-9.3, -1.0) | (8.3, 15.0) | (4.0, 10.3) | (-7.9, -1.0) | |||||