Fig. 2

MEGA-PRESS data processing. (A) The processed gamma-aminobutyric acid (GABA)-edited difference spectrum before frequency and phase correction (red) and after (blue). (B) The frequency of the maximum point in the residual water signal is plotted against time. (C) The y-axis represents the frequency (in ppm) of the Cr signal, before frequency-and-phase correction and after. (D) The GABA-edited spectrum is shown in blue. The model of best fit is shown in red. The residual between these two is shown in black. GABA, gamma-aminobutyric acid; Glx, glutamate/glutamine; Cr, creatine