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Fig. 4 | The Journal of Headache and Pain

Fig. 4

From: Gamma-aminobutyric acid and glutamate/glutamine levels in the dentate nucleus and periaqueductal gray in new daily persistent headache: a magnetic resonance spectroscopy study

Fig. 4

Correlation between clinical characteristics and neurotransmitter levels. (A) Negative correlation between Glx/Water in the PAG and the VAS score (r=-0.471, p = 0.031, n = 21). (B) Negative correlation between Glx/Water in the DN and the VAS score (r=-0.501, p = 0.021, n = 21). (C) Negative correlation between Glx/Cr in the DN and the VAS score (r=-0.483, p = 0.026, n = 21). (D) Positive correlation between GABA+/Water in the DN and the GAD-7 score (r = 0.519, p = 0.039, n = 16). Gray shading represents the 95% confidence intervals of the partial correlations. PAG, periaqueductal gray; DN, dentate nucleus; Cr, creatine; GABA, gamma-aminobutyric acid; Glx, glutamate/glutamine; VAS, Visual analog scale; GAD-7, Generalized Anxiety Disorder-7

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The Journal of Headache and Pain

ISSN: 1129-2377

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