Fig. 2

Serum (a) LPS, (b) HMGB1, (c) HIF-1α and (d) IL-6 levels were significantly higher in CM + MOH patients compared to healthy controls (p = 0.002, p = 0.023, p = 0.009 and p = 0.042 respectively). CM + MOH patients had higher (e) HADS-A and (f) HADS-D scores compared to healthy controls (p < 0.0001 and p < 0.0001 respectively). Data are shown as whisker-box plots (whisker: full range; line: median; cross: mean)