Fig. 3

Patient journey through pain states from baseline to 3-h, for those with moderate pain at baseline. Footnote: This figure tracks the path patients take through different pain severity states over 3-h. In this figure, at 0-min all patients have moderate pain (purple). The size of the colored band represents the number of people in those groups, with thicker bands representing a larger sample size. For example, at 15-min, most patients remain at a moderate pain state, but some patients begin to transition to mild (blue), severe (red) and no pain (green). As time progresses, a larger proportion of patients transition to other pain states