Fig. 4

Patient journey through pain states from baseline to 3-h, for those with severe pain at baseline. Footnote: This figure tracks the path patients take through different pain severity states over 3-h. In this figure, at 0-min all patients have severe pain (red). The size of the colored band represents the number of people in those groups, with thicker bands representing a larger sample size. For example, at 15-min, most patients from this group remain at severe pain state but some patients begin to transition to moderate (blue), mild (blue) and no pain (green) as early as 15-min. As time progresses, a larger proportion of patients transition to other pain states