Fig. 6

Patient journey through functional disability states from baseline to 3-h, for those with severe functional disability or bedrest at baseline. Footnote: This figure tracks the path patients take through different functional disability states over 3-h. In this figure, at 0-min all patients have severe functional disability /requires bedrest state (red). The size of the colored band represents the number of people in those groups, with thicker bands representing a larger sample size. For example, at 30-min, most patients remain at a severe functional disability/requires bedrest state but some patients begin to transition to a mildly impaired functional state (blue) or no functional impairment state (green). As time progresses, a larger proportion of patients transition to other pain states