Table 3 Mean hours spent in each pain severity state over 48-h period
Mean (SD) hours in pain state | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Complete case analysis | MNAR imputation analysis | |||||||||
Pain states | Zav (n = 327) | PBO (n = 303) | Mean difference | Cohen’s D | P-value | Zav (n = 623) | PBO (n = 646) | Mean difference | Cohen’s D | P-value |
None | 35.9 (13.7) | 33.1 (15.0) | + 2.8 | 0.195 | 0.016 | 26.9 (17.8) | 23.2 (18.0) | + 3.7 | 0.207 | < 0.001 |
Mild | 7.8 (9.6) | 9.5 (10.2) | − 1.7 | −0.172 | 0.033 | 9.9 (9.1) | 10.8 (9.6) | − 0.9 | −0.096 | 0.070 |
Moderate | 3.3 (6.4) | 4.4 (7.7) | − 1.1 | −0.155 | 0.050 | 8.7 (10.8) | 11.1 (12.3) | − 2.4 | −0.207 | < 0.001 |
Severe | 1.0 (3.7) | 1.0 (3.1) | 0 | 0.000 | 0.842 | 2.5 (4.8) | 2.9 (5.0) | − 0.4 | −0.082 | 0.188 |