Table 3 Efficacy of Onabotulinum toxin-A injection into the sphenopalatine ganglion on pain frequency
Time (days) | Pain frequency episodes per day, mean ± SD | Change in pain frequency episodes per day from baseline (95% CI) | p-value |
|---|---|---|---|
Pre-procedure | 12.15 ± 8.61 | Reference | |
10 | 4.31 ± 2.69 | -7.85 (-12.68, -3.01) | < 0.001 |
20 | 4.15 ± 3.89 | -8.00 (-11.97, -4.03) | < 0.001 |
30 | 3.54 ± 3.13 | -8.62 (-12.76, -4.47) | < 0.001 |
40 | 4.23 ± 4.04 | -7.92 (-11.53, -4.32) | < 0.001 |
50 | 4.08 ± 3.73 | -8.08 (-11.55, -4.60) | < 0.001 |
60 | 3.38 ± 2.53 | -8.77 (-13.02, -4.52) | < 0.001 |