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Table 2 Migraine and headaches among women who developed MS after MoBa inclusion and women without MS

From: Migraine in the multiple sclerosis prodrome: a prospective nationwide cohort study in pregnant women

 

Migraine

Other headaches

n (%)

aOR (95% CI)

P value

n (%)

aOR (95% CI)

P value

Preclinical MS n= 246

Years until MS symptom onset

43 (18)

1.6 (1.2–2.3)

0.006

71 (29)

1.1 (0.8–1.4)

0.63

 ≤ 5 years (n = 116)

21 (18)

1.7 (1.1–2.8)

0.029

35 (30)

1.2 (0.8–1.7)

0.50

 6–10 years (n = 92)

19 (21)

1.9 (1.1–3.2)

0.016

26 (28)

1.1 (0.7–1.7)

0.79

 > 10 years (n = 38)

3 (8)

0.7 (0.2–2.2)

0.53

10 (26)

0.9 (0.4–1.9)

0.72

Women without MS n = 85 292

9718 (11)

1.0 (ref.)

Ref

22 939 (27)

1.0 (ref.)

Ref

  1. Abbreviations: MS Multiple sclerosis, MoBa The Norwegian Mother, Father and Child Cohort study, aOR adjusted Odds Ratios, CI Confidence Interval. Preclinical MS = women who developed MS after MoBa inclusion who had not yet experienced classical MS symptom onset. Women with preclinical MS were compared to women who did not develop MS during follow-up. ORs are adjusted for age, smoking history, socioeconomic status, and overweight