Table 1 Patient demographics and disease characteristics at baseline

Age (years), mean (SD)

41.6 (12.1)

39.7 (11.9) *

41.1 (12.4)

Sex (female), %

86.6

85.3

81.6

Race (white), %

77.4

80.2

81.2

Duration of migraine disease (years), mean (SD)

21.9 (12.9)

20.4 (12.7)

20.1 (12.7) *

Number of comorbidities other than migraine,^a mean (SD)

4.4 (3.7)

4.1 (3.3)

4.2 (3.2)

Migraine headache days per month, mean (SD)

19.6 (4.6)

19.4 (4.3)

19.2 (4.6)

Headache days per month, mean (SD)

21.5 (4.1)

21.2 (4.0)

21.4 (4.1)

Migraine headache days with acute medication use per month, mean (SD)

15.5 (6.6)

15.1 (6.3)

14.5 (6.3) *

Severity of migraine headaches per month, mean (SD)^b

2.2 (0.4)

2.2 (0.4)

2.2 (0.4)

Prior migraine preventive treatment, %

78.0

75.9

79.4

Acute headache medication overuse during baseline period, %

63.4

64.3

64.1

MIDAS total score,^c mean (SD)

68.7 (57.4)

62.5 (49.5)

69.2 (64.1)

MSQ RF-R,^c mean (SD)

38.4 (17.2)

39.3 (17.3)

38.9 (17.3)