Table 1 Main characteristics and results of the included studies
From: Prediction models for treatment response in migraine: a systematic review and meta-analysis
Study | Disorder | Intervention | Outcome | Duration | N | Res/nRes | Modality | Model | Validation | C.index | Spec (%) | Sen (%) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Feng et al. (2022)[23] | MwoA | taVNS | Reduction in VAS score by 25% | 4 weeks | 120 | NR | rs-fMRI | SVR | 10-fold-CV x 1000 | prediction-outcome correlation(r) = 4.11 | NR | NR |
Gonzalez-Martinez et al. (2022)[24] | CM, MwoA, MwA | Anti-CGRP receptor or ligand antibody treatment | 30%/50%/75% reduction in the number of monthly headache days from baseline to months 6, 9 and 12 | 24/36/48weeks | 712 | 27/131 | Clinical data | RF | NR | AUC: 0.98, ACC: 0.97 | NR | 97 |
Liu et al. (2019)[12] | MwoA | Sham acupuncture treatment | Reduction in migraine days ≥ 50% | 8 weeks | 94 | 38/56 | DTI | LSVM | LOO CV | ACC: 0.84 | 77 | 92 |
Lu et al. (2022)[25] | Migraine | NSAIDs | Reduction in VAS scores by more than 50% | 12 weeks | 610 | 326/284 | Clinical data | LR, SVM, DT, MLP | 10-fold-CV | AUC: 0.74 | 82 | 66 |
Wei et al. (2022)[37] | MwoA | NSAIDs | Reduction in VAS scores by more than 50% | NR | 103 | 35/35 | rs-fMRI | MLR, SVM | 5-fold-CV | AUC: 0.90 | 88 | 83 |
Wei et al. (2024a)[38] | MwoA | NSAIDs | Reduction in VAS scores by more than 50% | 12 weeks | 96 | 32/32 | rs-fMRI | SVM | 10-fold-CV | AUC: 0.94 | 100 | 86 |
Wei et al. (2024b)[16] | Migraine | NSAIDs | Reduction in VAS scores by more than 50% | 12 weeks | 118 | 59/59 | rs-fMRI、sMRI | RF | 10-fold-CV | AUC: 0.71 | 65 | 67 |
Wu et al. (2022)[40] | MwoA, MwA | Sumatriptan treatment | Reduction in headache intensity from moderate or severe to none or mild within 2 h after the intake of sumatriptan | NR | 105 | 73/32 | sMRI | Classification and regression tree | NR | ACC: 0.69 | 85 | 58 |
Yang et al. (2020)[39] | MwoA | Acupuncture treatment | Reduction in the number of migraine days ≥ 50% | 4 weeks | 41 | 19/22 | sMRI | SVM | 10-fold-CVx10 | AUC: 0.79 | 85 | 73 |
Yin et al. (2020)[14] | MwoA | Acupuncture treatment | NR | 4 weeks | 106 | NR | rs-fMRI | SVR | 10-fold-CV | NR | NR | NR |