Fig. 2
From: Network meta-analysis comparing efficacy of different strategies on medication-overuse headache
Network of eligible comparisons for the network meta-analysis for efficacy. The width of the lines for each connection is proportional to the number of randomized controlled trials of each directly compared treatment regimens. The size of the nodes corresponds to the number of randomized participants (sample size). C control, B botox, W abrupt withdrawal, A anti-CGRP, P oral prevention(s), E additional education, Nb Nerve block, R restriction of overused medication < = 2 days/week. The treatment nodes include C (N = 674), B (N = 445), A (N = 77), P (N = 434), R + P (N = 419), R + P + A (N = 114), W (N = 339), W + B (N = 117), W + Nb (N = 35), W + P (N = 226), W + P + E (N = 40), and W + P + Nb (N = 27)