Table 9 Factors associated with BDI score

Duration (years)

3.46

2.79

2.32

1.82

2.68

2.98

3.69

3.96

0.76

0.52

ALS-FRS R

28.64

8.30

32.22

12.97

35.42

9.10

34.00

8.17

1.47

0.23

N

%

N

%

N

%

N

%

X^2**

P value

Sex

Male

11

73.3%

9

81.8%

19

82.6%

34

65.4%

2.72 FE

0.44

Female

4

26.7%

2

18.2%

4

17.4%

18

34.6%

Marital status

Married

9

60.0%

5

45.5%

15

65.2%

35

68.6%

2.24

0.55

Single

6

40.0%

6

54.5%

8

34.8%

16

31.4%

Age of onset (years)

< 25

3

23.1%

2

20.0%

1

4.8%

9

18.4%

4.99 FE

0.55

25–45

6

46.2%

6

60.0%

10

47.6%

20

40.8%

> 45

4

30.8%

2

20.0%

10

47.6%

20

40.8%

Site of Onset

Spinal

10

71.4%

5

45.5%

13

61.9%

38

79.2%

5.71 FE

0.12

Bulbar

4

28.6%

6

54.5%

8

38.1%

10

20.8%

Type S/F

Sporadic

10

66.7%

10

90.9%

20

87.0%

34

65.4%

5.71 FE

0.12

Familial

5

33.3%

1

9.1%

3

13.0%

18

34.6%

Need for nasogastric tube

No

9

81.8%

9

81.8%

16

80.0%

41

87.2%

1.16 FE

0.79

Yes

2

18.2%

2

18.2%

4

20.0%

6

12.8%

Need for ventilation support

No

11

100.0%

10

90.9%

18

90.0%

46

97.9%

3.21 FE

0.27

Yes

0

0.0%

1

9.1%

2

10.0%

1

2.1%

MIDAS

No disability

7

46.7%

2

18.2%

6

26.1%

18

34.6%

7.80 FE

0.53

Mild

5

33.3%

6

54.5%

12

52.2%

19

36.5%

Moderate

1

6.7%

2

18.2%

5

21.7%

11

21.2%

Severe

2

13.3%

1

9.1%

0

0.0%

4

7.7%

HIT6

Little or no impact

9

60.0%

4

36.4%

9

39.1%

21

40.4%

12.02 FE

0.17

Some impact

4

26.7%

1

9.1%

9

39.1%

19

36.5%

Substantial impact

0

0.0%

5

45.5%

4

17.4%

8

15.4%

Severe impact

2

13.3%

1

9.1%

1

4.3%

4

7.7%

Ambulation

No

5

33.3%

4

36.4%

8

34.8%

16

30.8%

0.38 FE

0.96

Yes

10

66.7%

7

63.6%

15

65.2%

36

69.2%

Currently working

No

5

33.3%

4

36.4%

9

39.1%

19

36.5%

0.13

0.99

Yes

10

66.7%

7

63.6%

14

60.9%

33

63.5%