Table 2 GRADE approach depicting the certainty of the evidence
From: Association between proton pump inhibitor use and migraine: a systematic review and meta-analysis
Certainty assessment | Effect | Certainty | Importance | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
No. of studies | Study design | Risk of bias | Inconsistency | Indirectness | Imprecision | Other considerations | Relative (95% CI) | Absolute (95% CI) | ||
Association between PPI use and migraine | ||||||||||
3 | Non-randomized studies | serious | serious | not serious | serious | none | OR 2.508 (0.790 to 7.969) | - | ⨁◯◯◯ Very low | CRITICAL |
0 fewer per 1,000 (from 0 fewer to 0 fewer) | ||||||||||