Table 2 Comparative analysis of the different headache diary parameters and functional impact scores

Number of Headache days

Initial

28.8 ± 1.07

28.18 ± 0.72

28.43 ± 0.74

0.117

0.890

Follow up

28.2 ± 2.66

13.68 ± 1.79

15.71 ± 1.84

10.787

< 0.001

Pairwise comparison

p-value

0.82

< 0.001

< 0.001

Duration in hours

Initial

24 ± 3.3

28.09 ± 2.23

22.43 ± 2.28

1.643

0.204

Follow up

24 ± 3.81

12.86 ± 2.57

10.92 ± 2.63

4.224

0.020

Pairwise comparison

p-value

1.00

< 0.001

< 0.001

Intensity

Initial

9.2 ± 0.29

9.09 ± 0.2

8.9 ± 0.2

0.403

0.670

Follow up

9.2 ± 0.53

5.14 ± 0.36

5.33 ± 0.37

22.422

< 0.001

Pairwise comparison

p-value

1.00

< 0.001

< 0.001

Total Pain Index

Initial

6348 ± 692.07

6954.55 ± 466.59

5746.29 ± 477.57

1.638

0.205

Follow up

6218.4 ± 555.18

1207.68 ± 374.3

1547.1 ± 383.11

31.094

< 0.001

Pairwise comparison

p-value

0.859

< 0.001

< 0.001

No. of Analgesic tablets

Initial

3.2 ± 0.62

4 ± 0.41

3.24 ± 0.42

1.019

0.368

Follow up

3.2 ± 0.28

1.55 ± 0.19

1.19 ± 0.19

18.582

< 0.001

Pairwise comparison

p-value

1.00

< 0.001

< 0.001

No. of days/month

Initial

28.8 ± 2

28.86 ± 1.35

25.95 ± 1.38

1.322

0.276

Follow up

28.2 ± 2.74

9.23 ± 1.85

9.38 ± 1.89

19.264

< 0.001

Pairwise comparison

p-value

0.834

< 0.001

< 0.001

MIDAS score in days

Initial

111.3 ± 17.19

108.27 ± 11.59

76.43 ± 11.87

2.316

0.109

Follow up

111.3 ± 14.63

38.09 ± 9.86

30.14 ± 10.09

11.424

< 0.001

Pairwise comparison

p-value

1.00

< 0.001

< 0.001

HIT-6 score

Initial

69.8 ± 1.34

72.91 ± 0.9

71.95 ± 0.92

1.862

0.166

Follow up

69.8 ± 3.3

54.95 ± 2.23

54.48 ± 2.28

8.480

0.001

Pairwise comparison

p-value

1.00

< 0.001

< 0.001