Table 5 Potential drug candidates and associated pathways for migraine therapy
From: The interictal transcriptomic map of migraine without aura
Drugs | Associated pathway(s) | Reference(s) (PMIDs) |
|---|---|---|
buclizine | Positive regulation of cell death, response to lipid, transmembrane receptor protein tyrosine kinase signalling pathway | 22469258 |
mecloxamine | Positive regulation of cell death | 17373440,9265005,8366753,6342291 |
verapamil | Positive regulation of cell death | 2668225 |
tetrandrine | Positive regulation of cell death | 29147842 |
olmesartan | Transmembrane receptor protein tyrosine kinase signaling pathway | 16618270,16942482,31515634 |
nicardipine | Cytokine mediated signaling pathway, innate immune response, phagocytosis, positive regulation of cell death, transmembrane receptor protein tyrosine kinase signaling pathway | 30600979,2245455 |
tubocurarine | Positive regulation of cell death, transmembrane receptor protein tyrosine kinase signaling pathway | 28496430,10686170 |
zafirlukast | Positive regulation of cell death | 17691939,15648777,10759916 |
opc-28326 | Positive regulation of cell death | 17103145 |
indoramin | Positive regulation of cell death | 49624,324566 |
nystatin | Positive regulation of cell death | 28041915 |
pasireotide | Positive regulation of cell death | 29925553 |
thioridazine | Transmembrane receptor protein tyrosine kinase signaling pathway | 10667670 |
bicuculline | Positive regulation of cell death | 36259130,12499053 |
bi 44370 ta | Positive regulation of cell death | 32525262 |
berberine | Transmembrane receptor protein tyrosine kinase signaling pathway | 23758551 |
resiniferatoxin | Positive regulation of cell death | 29187670,23155193 |
ondansetron | Positive regulation of cell death | 32433024,20661681 |
lomerizine | Transmembrane receptor protein tyrosine kinase signaling pathway | 37194515,29221971 |
eletriptan | Positive regulation of cell death | 15853473 |