Fig. 1
From: Unraveling the paradox: cardiovascular risk profiling in migraine– a correspondence
– A hypothesized overview of biological mechanisms involved in the association between the EC-specific polygenic risk score, migraine, and coronary artery disease. Green arrows and lines represent stimulatory or upregulated effects, while red arrows and lines indicate inhibitory or downregulated effects. Please note that this is a simplified model and does not capture the full complexity of the interactions and (causal) effects involved. Image was created using BioRender