Fig. 8

This is an overview of brain microstructural changes in migraine and its subtypes. Neurite damage is a pathological feature of migraine. With chronicity of migraine, axonal injury or demyelination becomes more severe. Across several brain regions, cortical neurites are diminished in both migraine and CM. The loss of cortical gray matter neurites is negative associated with neurotransmitters. It was created with http://www.biorender.com/. HC, Health control; EM, episodic migraine; CM, chronic migraine